These images show eggs of Schistosoma mansoni in unstained and stained (hematoxylin & eosin) tissue. The unstained preparation was created by pressing a rectal biopsy tissue between 2 glass slides, while the H&E-stained tissue sections were made from formalin-fixed paraffin-embedded tissue. Note that the eggs are large (114 to 180 micrometers long by 40 to 70 micrometers wide) and have a prominent lateral spine (arrow), although the spine is not seen in all of the tissue sections.